Giuliano Boscutti Selected Research

Lecithin Cholesterol Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency)

1/2022	The HDL mimetic CER-001 remodels plasma lipoproteins and reduces kidney lipid deposits in inherited lecithin:cholesterol acyltransferase deficiency.
1/2016	[Lecithin:Cholesterol Acyltransferase Deficiency, from genes to therapy].
5/2012	Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia.
7/2011	[LCAT deficiency: a nephrological diagnosis].
8/2009	Functional lecithin: cholesterol acyltransferase is not required for efficient atheroprotection in humans.
9/2005	The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families.

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Giuliano Boscutti Research Topics

Disease

6	Lecithin Cholesterol Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency) 01/2022 - 09/2005
2	Renal Insufficiency (Renal Failure) 01/2022 - 01/2018
2	Kidney Diseases (Kidney Disease) 01/2022 - 12/2019
2	Acute Kidney Injury (Acute Renal Failure) 09/2021 - 09/2008
2	Proteinuria 03/2021 - 12/2019
2	Membranous Glomerulonephritis (Membranous Nephropathy) 03/2021 - 12/2019
2	Dyslipidemias (Dyslipidemia) 01/2016 - 07/2011
2	Hypoalphalipoproteinemias (Hypoalphalipoproteinemia) 05/2012 - 08/2009
1	Acute Generalized Exanthematous Pustulosis 01/2020
1	Undifferentiated Connective Tissue Diseases 01/2020
1	Septic Shock (Toxic Shock Syndrome) 01/2019
1	Pulmonary Embolism 01/2018
1	Heart Failure 01/2018
1	Dyspnea (Shortness of Breath) 01/2018
1	Pneumonia (Pneumonitis) 01/2018
1	Vasculitis (Vasculitides) 01/2018
1	Respiratory Insufficiency (Respiratory Failure) 01/2018
1	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 01/2018
1	Essential Hypertension 12/2014
1	Chronic Renal Insufficiency 12/2014
1	Atrial Fibrillation 12/2014
1	Edema (Dropsy) 01/2014
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2014
1	Hypobetalipoproteinemias (Hypobetalipoproteinemia) 05/2012
1	Sclerosis 07/2011
1	Corneal Opacity 07/2011
1	Coronary Artery Disease (Coronary Atherosclerosis) 07/2011
1	Chronic Kidney Failure (Chronic Renal Failure) 07/2011
1	Anemia 07/2011
1	Atherosclerosis 08/2009
1	Visceral Leishmaniasis (Kala Azar) 09/2008
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 09/2008

Drug/Important Bio-Agent (IBA)

3	LipidsIBA 01/2022 - 07/2011
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/2021 - 01/2018
2	Lipoproteins (Lipoprotein)IBA 01/2022 - 01/2016
2	Rituximab (Mabthera)FDA Link 03/2021 - 12/2019
2	SteroidsIBA 03/2021 - 12/2019
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 09/2005
2	CholesterolIBA 05/2012 - 08/2009
2	HDL CholesterolIBA 07/2011 - 08/2009
2	Phosphatidylcholine-Sterol O-Acyltransferase (Lecithin Cholesterol Acyltransferase)IBA 07/2011 - 08/2009
1	CER-001IBA 01/2022
1	Heroin (Diamorphine)IBA 09/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2020
1	Alkylating AgentsIBA 12/2019
1	Citric Acid (Citrate)FDA LinkGeneric 01/2019
1	Antiviral Agents (Antivirals)IBA 01/2018
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2018
1	Acyclovir (Aciclovir)FDA LinkGeneric 01/2018
1	Warfarin (Coumadin)FDA LinkGeneric 12/2014
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2014
1	Proteins (Proteins, Gene)FDA Link 01/2014
1	nephrinIBA 01/2014
1	Apolipoproteins B (ApoB)IBA 05/2012
1	LDL CholesterolIBA 05/2012
1	Biomarkers (Surrogate Marker)IBA 07/2011
1	EnzymesIBA 08/2009
1	HDL LipoproteinsIBA 08/2009
1	liposomal amphotericin B FDA Link 09/2008

Therapy/Procedure

5	Therapeutics 03/2021 - 01/2016
1	Renal Dialysis (Hemodialysis) 01/2018
1	Enzyme Replacement Therapy 01/2016
1	Kidney Transplantation 05/2012